anti- GSTA2 antibody

Product Description

anti- GSTA2 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes function in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding these enzymes are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of some drugs. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-tranferase belonging to the alpha class. The alpha class genes, located in a cluster mapped to chromosome 6, are the most abundantly expressed glutathione S-transferases in liver. In addition to metabolizing bilirubin and certain anti- cancer drugs in the liver, the alpha class of these enzymes exhibit glutathione peroxidase activity thereby protecting the cells from reactive oxygen species and the products of peroxidation..

Immunogen: glutathione S-transferase alpha 2

Synonyms: Glutathione S transferase A2, GST class alpha member 2, GST gamma, GST HA subunit 2, GST2, GSTA2, GSTA2 2, GTA2, GTH2

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, WB, IHC

Recommended dilution: WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

Image 1: Immunohistochemistry of paraffin-embedded human prostate cancer using FNab03687(GSTA2 antibody) at dilution of 1:100

Image 2: .

Image 3:

Image 4: HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab03687(GSTA2 antibody) at dilution of 1:1000

Gene ID: 2939

Research Area: Metabolism

Uniprot ID: P09210