anti- H3F3B antibody

Product Description

anti- H3F3B antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: Variant histone H3 which replaces conventional H3 in a wide range of nucleosomes in active genes. Constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis. Deposited at sites of nucleosomal displacement throughout transcribed genes, suggesting that it represents an epigenetic imprint of transcriptionally active chromatin. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling..

Immunogen: H3 histone, family 3B(H3.3B)

Synonyms: H3.3B

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, WB

Recommended dilution:

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Image 4: HepG2 cells were subjected to SDS PAGE followed by western blot with FNab03740( H3F3B Antibody) at dilution of 1:600

Gene ID: 3021

Research Area: Metabolism

Uniprot ID: P84243