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Product Description
anti- HACE1 antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: E3 ubiquitin-protein ligase involved in Golgi membrane fusion and regulation of small GTPases. Acts as a regulator of Golgi membrane dynamics during the cell cycle: recruited to Golgi membrane by Rab proteins and regulates postmitotic Golgi membrane fusion. Acts by mediating ubiquitination during mitotic Golgi disassembly, ubiquitination serving as a signal for Golgi reassembly later, after cell division. Specifically interacts with GTP-bound RAC1, mediating ubiquitination and subsequent degradation of active RAC1, thereby playing a role in host defense against pathogens. May also act as a transcription regulator via its interaction with RARB..
Immunogen: HECT domain and ankyrin repeat containing, E3 ubiquitin protein ligase 1
Synonyms: KIAA1320
Reactivity: Human
Tested Application: ELISA, WB, IF
Recommended dilution:
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Image 4: HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab03745( HACE1 Antibody) at dilution of 1:600
Gene ID: 57531
Research Area: Metabolism
Uniprot ID: Q8IYU2
