Product Description
anti- HCFC1 antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: Involved in control of the cell cycle. Also antagonizes transactivation by ZBTB17 and GABP2; represses ZBTB17 activation of the p15(INK4b) promoter and inhibits its ability to recruit p300. Coactivator for EGR2 and GABP2. Tethers the chromatin modifying Set1/Ash2 histone H3 'Lys-4' methyltransferase(H3K4me) and Sin3 histone deacetylase(HDAC) complexes(involved in the activation and repression of transcription, respectively) together. Component of a THAP1/THAP3-HCFC1-OGT complex that is required for the regulation of the transcriptional activity of RRM1. As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. In case of human herpes simplex virus(HSV) infection, HCFC1 forms a multiprotein-DNA complex with the viral transactivator protein VP16 and POU2F1 thereby enabling the transcription of the viral immediate early genes..
Immunogen: host cell factor C1(VP16-accessory protein)
Synonyms: HCF1, HFC1
Reactivity: Human, Mouse, Rat
Tested Application: ELISA, WB, IHC
Recommended dilution:
Image 1: Immunohistochemistry of paraffin-embedded human colon cancer using FNab03782(HCFC1 antibody) at dilution of 1:50
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Image 4: HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab03782(HCFC1 antibody) at dilution of 1:500
Gene ID: 3054
Research Area: Metabolism
Uniprot ID: P51610