anti- HINT1 antibody

Product Description

anti- HINT1 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: Hydrolyzes purine nucleotide phosphoramidates with a single phosphate group, including adenosine 5'monophosphoramidate(AMP-NH2), adenosine 5'monophosphomorpholidate(AMP-morpholidate) and guanosine 5'monophosphomorpholidate(GMP-morpholidate). Hydrolyzes lysyl-AMP(AMP-N-epsilon-(N-alpha-acetyl lysine methyl ester)) generated by lysine tRNA ligase, as well as Met-AMP, His-AMP and Asp-AMP, lysyl-GMP(GMP-N-epsilon-(N-alpha-acetyl lysine methyl ester)) and AMP-N-alanine methyl ester. Can also convert adenosine 5'-O-phosphorothioate and guanosine 5'-O-phosphorothioate to the corresponding nucleoside 5'-O-phosphates with concomitant release of hydrogen sulfide. In addition, functions as scaffolding protein that modulates transcriptional activation by the LEF1/TCF1-CTNNB1 complex and by the complex formed with MITF and CTNNB1. Modulates p53/TP53 levels and p53/TP53-mediated apoptosis. Modulates proteasomal degradation of target proteins by the SCF(SKP2-CUL1-F-box protein) E3 ubiquitin-protein ligase complex..

Immunogen: histidine triad nucleotide binding protein 1

Synonyms: HINT, PKCI1, PRKCNH1

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, WB, IHC, IP

Recommended dilution:

Image 1: Immunohistochemistry of paraffin-embedded human colon cancer tissue slide using FNab03866(HINT1 Antibody) at dilution of 1:400 heat mediated antigen retrieved with Tris-EDTA buffer(pH9).

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Image 4: HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab03866(HINT1 antibody) at dilution of 1:400

Gene ID: 3094

Research Area: Metabolism

Uniprot ID: P49773