anti- HLA-G antibody

Product Description

anti- HLA-G antibody is available at Gentaur for Next week Delivery.

Purification: protein A+G purified

Background: Human major histocompatibility complex (MHC) antigens, also referred to as human leukocyte antigens (HLA), are encoded by genes located on the short arm of chromosome 6 (6p21.3). HLA-G is a non-classical MHC class I molecule with multiple immunoregulatory properties. HLA-G exhibits a restricted pattern of expression that includes placental extravillous trophoblasts at the maternal-fetal interface, where it abolishes maternal immune cell activity against fetus and establishes immune tolerance. Aberrant expression of HLA-G has been found in a variety of human neoplastic diseases. It plays an important role in the escape of tumor cells from immunosurveillance..

Immunogen: MHC class I antigen G

Synonyms: HLA 6.0, HLA G, HLA G antigen, HLAG, HLA-G, MHC class I antigen G, MHC G

Reactivity: Human

Tested Application: ELISA, WB, IHC

Recommended dilution: WB: 1:2000-1:10000; IHC: 1:50-1:200

Image 1: Immunohistochemistry of paraffin-embedded human placenta tissue slide using FNab09952( HLA-G Antibody) at dilution of 1:200

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Image 4: human placenta tissue were subjected to SDS PAGE followed by western blot with FNab09952( HLA-G Antibody) at dilution of 1:5000

Gene ID: 3135

Research Area: Metabolism

Uniprot ID: P17693