Product Description
anti- HOMER1 antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: Postsynaptic density scaffolding protein. Binds and cross-links cytoplasmic regions of GRM1, GRM5, ITPR1, DNM3, RYR1, RYR2, SHANK1 and SHANK3. By physically linking GRM1 and GRM5 with ER-associated ITPR1 receptors, it aids the coupling of surface receptors to intracellular calcium release. May also couple GRM1 to PI3 kinase through its interaction with AGAP2. Isoform 1 regulates the trafficking and surface expression of GRM5. Isoform 3 acts as a natural dominant negative, in dynamic competition with constitutively expressed isoform 1 to regulate synaptic metabotropic glutamate function. Isoform 3, may be involved in the structural changes that occur at synapses during long-lasting neuronal plasticity and development..
Immunogen: homer homolog 1(Drosophila)
Synonyms: SYN47
Reactivity: Human, Mouse
Tested Application: ELISA, WB, FC, IHC, IP
Recommended dilution:
Image 1: Immunohistochemistry of paraffin-embedded mouse brain tissue slide using FNab03963(HOMER1 Antibody) at dilution of 1:50
Image 2: .
Image 3:
Image 4: human brain tissue were subjected to SDS PAGE followed by western blot with FNab03963(HOMER1 antibody) at dilution of 1:1000
Gene ID: 9456
Research Area: Metabolism
Uniprot ID: Q86YM7