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Product Description
anti- HP antibody is available at Gentaur for Next week Delivery.
Purification: Protein A+G purification
Background: As a result of hemolysis, hemoglobin is found to accumulate in the kidney and is secreted in the urine. Haptoglobin captures, and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to prevent kidney damage. Haptoglobin also acts as an Antimicrobial; Antioxidant, has antibacterial activity and plays a role in modulating many aspects of the acute phase response. Hemoglobin/haptoglobin complexes are rapidely cleared by the macrophage CD163 scavenger receptor expressed on the surface of liver Kupfer cells through an endocytic lysosomal degradation pathway. Uncleaved haptoglogin, also known as zonulin, plays a role in intestinal permeability, allowing intercellular tight junction disassembly, and controlling the equilibrium between tolerance and immunity to non-self antigens..
Immunogen: haptoglobin
Synonyms: BP, HAPT, haptoglobin, HP, HP2 ALPHA 2, HPA1S, Zonulin
Reactivity: Human, Pig
Tested Application: ELISA, WB
Recommended dilution: WB: 1:2000 - 1:20000
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Image 4: 0.5 ?l human plasma was subjected to SDS PAGE followed by western blot with FNab03990 (HP Antibody) at dilution of 1:20000
Gene ID: 3240
Research Area: Metabolism
Uniprot ID: P00738
