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Product Description
anti- HSP70 antibody is available at Gentaur for Next week Delivery.
Purification: Protein A+G purification
Background: HSPA1A, collectively known as HSP70(also referred to HSP72), is a stress-inducible member of heat-shock protein 70(HSP70) proteins which are highly conserved chaperons implicated in protein folding, protein refolding, protein transport, and protein targeting. Encoded by two closely linked, intronless and stress-inducible genes, HSPA1A and HSPA1B differ by only two amino acids and are believed to be fully interchangeable proteins. HSPA1A is a cytosol/nuclear protein able to translocate between cytoplasm and nucleus. Generally, HSPA1A is thought to be expressed in unstressed normal cells at low or undetectable levels. Expression of HSPA1A protein can be highly activated by various stressful stimuli. Significant up-regulation of HSPA1A has been found in various tumors. Recently it has been reported that HSPA1A can be constitutively expressed in selected cell types. HSP70 is a useful marker for exosome. This antibody well recognized the endogenous HSP70 protein in multiple cell lines.(21373891).
Immunogen: heat shock 70kDa protein 1A
Synonyms: Heat shock 70 kDa protein 1A,HSPA1A,Heat shock 70 kDa protein 1,HSP70-1,HSPA1, HSX70
Reactivity: Human, Mouse, Rat
Tested Application: ELISA, WB,IHC
Recommended dilution: WB: 1:2000-1:40000 IHC: 1:50-1:500
Image 1: Immunohistochemistry of paraffin-embedded human breast cancer tissue slide using FNab04050(HSP70 Antibody) at dilution of 1:20
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Image 4: HeLa cells were subjected to SDS PAGE followed by western blot with FNab04050(HSP70 Antibody) at dilution of 1:10000
Research Area: Metabolism
Uniprot ID: P0DMV8
