anti- IFIT2 antibody

Product Description

anti- IFIT2 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: IFN-induced antiviral protein which inhibits expression of viral messenger RNAs lacking 2'-O-methylation of the 5' cap. The ribose 2'-O-methylation would provide a molecular signature to distinguish between self and non-self mRNAs by the host during viral infection. Viruses evolved several ways to evade this restriction system such as encoding their own 2'-O-methylase for their mRNAs or by stealing host cap containing the 2'-O-methylation(cap snatching mechanism). Binds AU-rich viral RNAs, with or without 5' triphosphorylation, RNA-binding is required for antiviral activity. Can promote apoptosis..

Immunogen: interferon-induced protein with tetratricopeptide repeats 2

Synonyms: cig42, G10P2, GARG 39, IFI 54, IFI 54K, IFI54, IFIT 2, IFIT2, ISG 54 K, ISG 54K, ISG54

Reactivity: Human, Mouse

Tested Application: ELISA, WB, IHC, IF

Recommended dilution: WB: 1:200-1:1000; IHC: 1:50-1:500; IF: 1:10-1:100

Image 1: Immunohistochemistry of paraffin-embedded human kidney tissue slide using FNab04137(IFIT2 Antibody) at dilution of 1:50

Image 2: Immunofluorescent analysis of HepG2 cells using FNab04137 (IFIT2 antibody) at dilution of 1:25 and Alexa Fluor 488-conjugated Goat Anti-Rabbit IgG(H+L).

Image 3:

Image 4: A431 cells were subjected to SDS PAGE followed by western blot with FNab04137(IFIT2 Antibody) at dilution of 1:300

Gene ID: 3433

Research Area: Metabolism

Uniprot ID: P09913