Product Description
anti- IFITM1 antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: IFN-induced antiviral protein which inhibits the entry of viruses to the host cell cytoplasm, permitting endocytosis, but preventing subsequent viral fusion and release of viral contents into the cytosol. Active against multiple viruses, including influenza A virus, SARS coronavirus(SARS-CoV), Marburg virus(MARV), Ebola virus(EBOV), Dengue virus(DNV), West Nile virus(WNV), human immunodeficiency virus type 1(HIV-1) and hepatitis C virus(HCV). Can inhibit: influenza virus hemagglutinin protein-mediated viral entry, MARV and EBOV GP1,2-mediated viral entry and SARS-CoV S protein-mediated viral entry. Also implicated in cell adhesion and control of cell growth and migration. Plays a key role in the antiproliferative action of IFN-gamma either by inhibiting the ERK activation or by arresting cell growth in G1 phase in a p53-dependent manner. Acts as a positive regulator of osteoblast differentiation..
Immunogen: interferon induced transmembrane protein 1(9-27)
Synonyms: CD225, IFI17
Reactivity: Human
Tested Application: ELISA, WB, IHC, IP
Recommended dilution:
Image 1: Immunohistochemistry of paraffin-embedded human lymphoma using FNab04140(IFITM1 antibody) at dilution of 1:50
Image 2: .
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Image 4: K-562 cells were subjected to SDS PAGE followed by western blot with FNab04140(IFITM1 antibody) at dilution of 1:500
Gene ID: 8519
Research Area: Metabolism
Uniprot ID: P13164