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Product Description
anti- IFT57 antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: Required for the formation of cilia. Plays an indirect role in sonic hedgehog signaling, cilia being required for all activity of the hedgehog pathway(By similarity). Has pro-apoptotic function via its interaction with HIP1, leading to recruit caspase-8(CASP8) and trigger apoptosis. Has the ability to bind DNA sequence motif 5'-AAAGACATG-3' present in the promoter of caspase genes such as CASP1, CASP8 and CASP10, suggesting that it may act as a transcription regulator; however the relevance of such function remains unclear..
Immunogen: intraflagellar transport 57 homolog(Chlamydomonas)
Synonyms: DERP8, ESRRBL1, HIPPI
Reactivity: Human, Mouse, Rat
Tested Application: ELISA, WB, IHC, IP
Recommended dilution:
Image 1: Immunohistochemistry of paraffin-embedded human prostate cancer using FNab04160(IFT57 antibody) at dilution of 1:50
Image 2: .
Image 3:
Image 4: mouse retina tissue were subjected to SDS PAGE followed by western blot with FNab04160(IFT57 antibody) at dilution of 1:1000
Gene ID: 55081
Research Area: Metabolism
Uniprot ID: Q9NWB7
