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Product Description
anti- IGHD antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: IgD is the major antigen receptor isotype on the surface of most peripheral B-cells, where it is coexpressed with IgM. The membrane-bound IgD(mIgD) induces the phosphorylation of CD79A and CD79B by the Src family of protein tyrosine kinases. Soluble IgD(sIgD) concentration in serum below those of IgG, IgA, and IgM but much higher than that of IgE. IgM and IgD molecules present on B cells have identical V regions and antigen-binding sites. After the antigen binds to the B-cell receptor, the secreted form sIgD is shut off. IgD is a potent inducer of TNF, IL1B, and IL1RN. IgD also induces release of IL6, IL10, and LIF from peripheral blood mononuclear cells. Monocytes seem to be the main producers of cytokines in vitro in the presence of IgD..
Immunogen: immunoglobulin heavy constant delta
Synonyms:
Reactivity: Human
Tested Application: ELISA, WB, IHC
Recommended dilution:
Image 1: Immunohistochemistry of paraffin-embedded human tonsillitis tissue slide using FNab04183(IGHD Antibody) at dilution of 1:50
Image 2: .
Image 3:
Image 4: Raji cells were subjected to SDS PAGE followed by western blot with FNab04183(IGHD antibody) at dilution of 1:600
Research Area: Metabolism
Uniprot ID: P01880
