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Product Description
anti- IGHM antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: IgM antibodies play an important role in primary defense mechanisms. They have been shown to be involved in early recognition of external invaders like bacteria and viruses, cellular waste and modified self, as well as in recognition and elimination of precancerous and cancerous lesions. The membrane-bound form is found in the majority of normal B-cells alongside with IgD. Membrane-bound IgM induces the phosphorylation of CD79A and CD79B by the Src family of protein tyrosine kinases. It may cause death of cells by apoptosis. It is also found in soluble form, which represents about 30% of the total serum immunoglobulins where it is found almost exclusively as a homopentamer. After the antigen binds to the B-cell receptor, the secreted form is secreted in large amounts..
Immunogen: immunoglobulin heavy constant mu
Synonyms:
Reactivity: Human
Tested Application: ELISA, WB
Recommended dilution:
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Image 4: human plasma tissue were subjected to SDS PAGE followed by western blot with FNab04185( IGHM Antibody) at dilution of 1:1000
Research Area: Metabolism
Uniprot ID: P01871
