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Product Description
anti- IL12B antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. Associates with IL23A to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis..
Immunogen: interleukin 12B
Synonyms: CLMF, CLMF p40, CLMF2, IL 12 subunit p40, IL 12B, IL12B, Interleukin 12 subunit beta, NKSF, NKSF2
Reactivity: Human
Tested Application: ELISA, WB
Recommended dilution: WB: 1:500-1:2000
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Image 4: A549 cells were subjected to SDS PAGE followed by western blot with FNab04219(IL12B Antibody) at dilution of 1:1000
Gene ID: 3593
Research Area: Metabolism
Uniprot ID: P29460
