anti- IL1R2 antibody

Product Description

anti- IL1R2 antibody is available at Gentaur for Next week Delivery.

Purification: Protein A+G purification

Background: Non-signaling receptor for IL1A, IL1B and IL1RN. Reduces IL1B activities. Serves as a decoy receptor by competetive binding to IL1B and preventing its binding to IL1R1. Also modulates cellular response through non-signaling association with IL1RAP after binding to IL1B. IL1R2(membrane and secreted forms) preferentially binds IL1B and poorly IL1A and IL1RN. The secreted IL1R2 recruits secreted IL1RAP with high affinity; this complex formation may be the dominant mechanism for neutralization of IL1B by secreted/soluble receptors..

Immunogen: interleukin 1 receptor, type II

Synonyms: CD121b, CDw121b, IL 1R 2, IL 1R beta, IL 1RT 2, IL 1RT2, IL1 Receptor 2, IL-1 Receptor 2, IL1 Receptor II, IL-1 Receptor II, IL1R2, IL1RB, IL-1RII, Interleukin 1 receptor beta, Interleukin 1 receptor type 2, Interleukin 1 receptor type II

Reactivity: Human, Mouse

Tested Application: ELISA, WB, IF

Recommended dilution: WB: 1:500-1:2000; IF: 1:20-1:200

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Image 4: HeLa cells were subjected to SDS PAGE followed by western blot with FNab04243(IL1R2 antibody) at dilution of 1:1000

Gene ID: 7850

Research Area: Metabolism

Uniprot ID: P27930