anti- ILF3 antibody

Product Description

anti- ILF3 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: This gene encodes a double-stranded RNA (dsRNA) binding protein that complexes with other proteins, dsRNAs, small noncoding RNAs, and mRNAs to regulate gene expression and stabilize mRNAs. This protein (NF90, ILF3) forms a heterodimer with a 45 kDa transcription factor (NF45, ILF2) required for T-cell expression of interleukin 2. This complex has been shown to affect the redistribution of nuclear mRNA to the cytoplasm. Knockdown of NF45 or NF90 protein retards cell growth, possibly by inhibition of mRNA stabilization. In contrast, an isoform (NF110) of this gene that is predominantly restricted to the nucleus has only minor effects on cell growth when its levels are reduced. Alternative splicing results in multiple transcript variants encoding distinct isoforms..

Immunogen: interleukin enhancer binding factor 3, 90kDa

Synonyms: DRBF, MPHOSPH4, NF90

Reactivity: Human, Mouse

Tested Application: ELISA, IHC, WB

Recommended dilution: WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

Image 1: Immunohistochemistry of paraffin-embedded human cervical cancer using FNab04288(NF90, ILF3 antibody) at dilution of 1:100

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Image 4: mouse spleen tissue were subjected to SDS PAGE followed by western blot with FNab04288( NF90, ILF3 Antibody) at dilution of 1:1000

Gene ID: 3609

Research Area: Metabolism

Uniprot ID: Q12906