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Product Description
anti- Integrin alpha-5 antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: Integrin alpha-5/beta-1 is a receptor for fibronectin and fibrinogen. It recognizes the sequence R-G-D in its ligands. ITGA5:ITGB1 binds to PLA2G2A via a site(site 2) which is distinct from the classical ligand-binding site(site 1) and this induces integrin conformational changes and enhanced ligand binding to site 1(PubMed:18635536, PubMed:25398877). ITGA5:ITGB1 acts as a receptor for fibrillin-1(FBN1) and mediates R-G-D-dependent cell adhesion to FBN1(PubMed:12807887, PubMed:17158881)..
Immunogen: integrin, alpha 5
Synonyms: CD49e, FNRA, Integrin alpha 5, Integrin alpha F, ITGA5, VLA 5, VLA5A
Reactivity: Human, Rat, Mouse, Monkey
Tested Application: ELISA, WB
Recommended dilution: WB: 1:500-1:2000
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Image 4: 3T3-L1 cells were subjected to SDS PAGE followed by western blot withFNab04347(ITGA5 antibody) at dilution of 1:1000
Research Area: Metabolism
Uniprot ID: P08648
