Product Description
anti- KANK2 antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: Involved in transcription regulation by sequestering nuclear receptor coactivators, such as NCOA1, NCOA2 and NCOA3, in the cytoplasm; the function is deregulated by phosphorylation. Involved in the negative control of vitamin D receptor signaling pathway(PubMed:24671081). May be involved in the control of cytoskeleton formation by regulating actin polymerization. Involved in regulation of caspase-independent apoptosis; proposed to sequester AIFM1 in mitochondria and apoptotic stimuli lead to its proteasomal degradation allowing the release of AIFM1 to the nucleus(PubMed:22371500). May be involved in promotion of cell proliferation(By similarity)..
Immunogen: KN motif and ankyrin repeat domains 2
Synonyms: ANKRD25, KIAA1518, MXRA3, SIP
Reactivity: Human, Mouse, Rat
Tested Application: ELISA, WB, IF
Recommended dilution:
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Image 4: mouse lung tissue were subjected to SDS PAGE followed by western blot with FNab04465(KANK2 antibody) at dilution of 1:800
Gene ID: 25959
Research Area: Metabolism
Uniprot ID: Q63ZY3