anti- KCNAB2 antibody

Product Description

anti- KCNAB2 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: Cytoplasmic potassium channel subunit that modulates the characteristics of the channel-forming alpha-subunits(PubMed:7649300, PubMed:11825900). Contributes to the regulation of nerve signaling, and prevents neuronal hyperexcitability(By similarity). Promotes expression of the pore-forming alpha subunits at the cell membrane, and thereby increases channel activity(By similarity). Promotes potassium channel closure via a mechanism that does not involve physical obstruction of the channel pore(PubMed:7649300, PubMed:11825900). Promotes KCNA4 channel closure(PubMed:7649300, PubMed:11825900). Modulates the functional properties of KCNA5(By similarity). Enhances KCNB2 channel activity(By similarity). Binds NADPH and has NADPH-dependent aldoketoreductase activity(By similarity). Has broad substrate specificity and can catalyze the reduction of methylglyoxal, 9,10-phenanthrenequinone, prostaglandin J2, 4-nitrobenzaldehyde, 4-nitroacetophenone and 4-oxo-trans-2-nonenal(in vitro)(By similarity)..

Immunogen: potassium voltage-gated channel, shaker-related subfamily, beta member 2

Synonyms: KCNA2B, KCNK2

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, WB

Recommended dilution: WB: 1:500 - 1:2000

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Image 4: HepG2 cells were subjected to SDS PAGE followed by western blot with FNab04479 (KCNAB2 antibody) at dilution of 1:1000

Gene ID: 8514

Research Area: Metabolism

Uniprot ID: Q13303