anti- KCNIP3 antibody

Product Description

anti- KCNIP3 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: Calcium-dependent transcriptional repressor that binds to the DRE element of genes including PDYN and FOS. Affinity for DNA is reduced upon binding to calcium and enhanced by binding to magnesium. Seems to be involved in nociception(By similarity). Regulatory subunit of Kv4/D(Shal)-type voltage-gated rapidly inactivating A-type potassium channels, such as KCND2/Kv4.2 and KCND3/Kv4.3. Modulates channel expression at the cell membrane, gating characteristics, inactivation kinetics and rate of recovery from inactivation in a calcium-dependent and isoform-specific manner. May play a role in the regulation of PSEN2 proteolytic processing and apoptosis. Together with PSEN2 involved in modulation of beta-amyloid formation..

Immunogen: Kv channel interacting protein 3, calsenilin

Synonyms: CSEN, DREAM, KCHIP3

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, WB, IHC

Recommended dilution:

Image 1: Immunohistochemistry of paraffin-embedded human gliomas using FNab04488(KCNIP3 antibody) at dilution of 1:50

Image 2: .

Image 3:

Image 4: human brain tissue were subjected to SDS PAGE followed by western blot with FNab04488(KCNIP3 antibody) at dilution of 1:500

Gene ID: 30818

Research Area: Metabolism

Uniprot ID: Q9Y2W7