anti- KCNK18 antibody

Product Description

anti- KCNK18 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: Outward rectifying potassium channel. Produces rapidly activating outward rectifier K(+) currents. May function as background potassium channel that sets the resting membrane potential. Channel activity is directly activated by calcium signal. Activated by the G(q)-protein coupled receptor pathway. The calcium signal robustly activates the channel via calcineurin, whereas the anchoring of 14-3-3/YWHAH interferes with the return of the current to the resting state after activation. Inhibited also by arachidonic acid and other naturally occurring unsaturated free fatty acids. Channel activity is also enhanced by volatile anesthetics, such as isoflurane. Appears to be the primary target of hydroxy-alpha-sanshool, an ingredient of Schezuan pepper. May be involved in the somatosensory function with special respect to pain sensation(By similarity)..

Immunogen: potassium channel, subfamily K, member 18

Synonyms: TRESK, TRIK

Reactivity: Human

Tested Application: ELISA, WB

Recommended dilution:

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Image 4: A431 cells were subjected to SDS PAGE followed by western blot with FNab04494( KCNK18 Antibody) at dilution of 1:1000

Gene ID: 338567

Research Area: Metabolism

Uniprot ID: Q7Z418