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Product Description
anti- KDM2A antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: Histone demethylase that specifically demethylates 'Lys-36' of histone H3, thereby playing a central role in histone code. Preferentially demethylates dimethylated H3 'Lys-36' residue while it has weak or no activity for mono-and tri-methylated H3 'Lys-36'. May also recognize and bind to some phosphorylated proteins and promote their ubiquitination and degradation. Required to maintain the heterochromatic state. Associates with centromeres and represses transcription of small non-coding RNAs that are encoded by the clusters of satellite repeats at the centromere. Required to sustain centromeric integrity and genomic stability, particularly during mitosis..
Immunogen: lysine(K)-specific demethylase 2A
Synonyms: CXXC8, FBL7, FBXL11, JHDM1A, KIAA1004
Reactivity: Human, Mouse
Tested Application: ELISA, WB
Recommended dilution:
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Image 4: Jurkat cells were subjected to SDS PAGE followed by western blot with FNab04509( KDM2A Antibody) at dilution of 1:1000
Gene ID: 22992
Research Area: Metabolism
Uniprot ID: Q9Y2K7
