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Product Description
anti- KDM5C antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: Histone demethylase that specifically demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9', H3 'Lys-27', H3 'Lys-36', H3 'Lys-79' or H4 'Lys-20'. Demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-4'. Participates in transcriptional repression of neuronal genes by recruiting histone deacetylases and REST at neuron-restrictive silencer elements. Represses the CLOCK-ARNTL/BMAL1 heterodimer-mediated transcriptional activation of the core clock component PER2(By similarity)..
Immunogen: lysine(K)-specific demethylase 5C
Synonyms: DXS1272E, JARID1C, SMCX, XE169
Reactivity: Human, Mouse, Rat
Tested Application: ELISA, WB
Recommended dilution:
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Image 4: HeLa cells were subjected to SDS PAGE followed by western blot with FNab04513(KDM5C antibody) at dilution of 1:500
Gene ID: 8242
Research Area: Metabolism
Uniprot ID: P41229
