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Product Description
anti- KEAP1 antibody is available at Gentaur for Next week Delivery.
Purification: Protein A+G purification
Background: Acts as a substrate adapter protein for the E3 ubiquitin ligase complex formed by CUL3 and RBX1 and targets NFE2L2/NRF2 for ubiquitination and degradation by the proteasome, thus resulting in the suppression of its transcriptional activity and the repression of antioxidant response element-mediated detoxifying enzyme gene expression. Retains NFE2L2/NRF2 and may also retain BPTF in the cytosol. Targets PGAM5 for ubiquitination and degradation by the proteasome..
Immunogen: kelch-like ECH-associated protein 1
Synonyms: INRF2, KIAA0132, KLHL19
Reactivity: Human, Mouse, Rat
Tested Application: ELISA, IHC, WB, IF
Recommended dilution: WB: 1:500-1:1000; IHC: 1:50-1:500; IF: 1:10-1:100
Image 1: Immunohistochemistry of paraffin-embedded human pancreas cancer using FNab04517(KEAP1 antibody) at dilution of 1:100
Image 2: .
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Image 4: HeLa cells were subjected to SDS PAGE followed by western blot with FNab04517(KEAP1 antibody) at dilution of 1:500
Gene ID: 9817
Research Area: Metabolism
Uniprot ID: Q14145
