anti- KLC1 antibody

Product Description

anti- KLC1 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: Conventional kinesin is a tetrameric molecule composed of two heavy chains and two light chains, and transports various cargos along microtubules toward their plus ends. The heavy chains provide the motor activity, while the light chains bind to various cargos. This gene encodes a member of the kinesin light chain family. It associates with kinesin heavy chain through an N-terminal domain, and six tetratricopeptide repeat (TPR) motifs are thought to be involved in binding of cargos such as vesicles, mitochondria, and the Golgi complex. Thus, kinesin light chains function as adapter molecules and not motors per se. Although previously named "kinesin 2", this gene is not a member of the kinesin-2 / kinesin heavy chain subfamily of kinesin motor proteins. Extensive alternative splicing produces isoforms with different C-termini that are proposed to bind to different cargos; however, the full-length nature and/or biological validity of most of these variants have not been determined..

Immunogen: kinesin light chain 1

Synonyms: KLC, KNS2

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, WB, IHC, IF

Recommended dilution: WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200

Image 1: Immunofluorescence analysis of U2OS cells using FNab04594(KLC1 antibody) at dilution of 1:100

Image 2: Immunofluorescence analysis of U2OS cells using FNab04594(KLC1 antibody) at dilution of 1:100.

Image 3:

Image 4: mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab04594(KLC1 antibody) at dilution of 1:1000

Gene ID: 3831

Research Area: Metabolism

Uniprot ID: Q07866