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Product Description
anti- KLHL22 antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: Substrate-specific adapter of a BCR(BTB-CUL3-RBX1) E3 ubiquitin ligase complex required for chromosome alignment and localization of PLK1 at kinetochores. The BCR(KLHL22) ubiquitin ligase complex mediates monoubiquitination of PLK1, leading to PLK1 dissociation from phosphoreceptor proteins and subsequent removal from kinetochores, allowing silencing of the spindle assembly checkpoint(SAC) and chromosome segregation. Monoubiquitination of PLK1 does not lead to PLK1 degradation..
Immunogen: kelch-like 22(Drosophila)
Synonyms:
Reactivity: Human, Mouse, Rat
Tested Application: ELISA, WB
Recommended dilution:
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Image 4: mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab04620(KLHL22 antibody) at dilution of 1:3000
Gene ID: 84861
Research Area: Metabolism
Uniprot ID: Q53GT1
