anti- KPNA6 antibody

Product Description

anti- KPNA6 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore. The protein encoded by this gene is a member of the importin alpha family..

Immunogen: karyopherin alpha 6 (importin alpha 7)

Synonyms: IPOA7

Reactivity: Human, Mouse

Tested Application: ELISA, IHC, WB

Recommended dilution: WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

Image 1: Immunohistochemistry of paraffin-embedded human kidney using FNab04638( KPNA6 Antibody) at dilution of 1:100 heat mediated antigen retrieved with Tris-EDTA buffer(pH9).

Image 2: .

Image 3:

Image 4: BxPC-3 cells were subjected to SDS PAGE followed by western blot with FNab04638( KPNA6 Antibody) at dilution of 1:1000

Gene ID: 23633

Research Area: Metabolism

Uniprot ID: O60684