anti- LAT antibody

Product Description

anti- LAT antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: Required for TCR(T-cell antigen receptor)-and pre-TCR-mediated signaling, both in mature T-cells and during their development. Involved in FCGR3(low affinity immunoglobulin gamma Fc region receptor III)-mediated signaling in natural killer cells and FCER1(high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. Couples activation of these receptors and their associated kinases with distal intracellular events such as mobilization of intracellular calcium stores, PKC activation, MAPK activation or cytoskeletal reorganization through the recruitment of PLCG1, GRB2, GRAP2, and other signaling molecules..

Immunogen: linker for activation of T cells

Synonyms: LAT, LAT1, p36 38, pp36

Reactivity: Human, Mouse

Tested Application: ELISA, WB, IHC

Recommended dilution: WB: 1:500-1:2000; IHC: 1:50-1:500

Image 1: Immunohistochemistry of paraffin-embedded mouse spleen using FNab10030(LAT antibody) at dilution of 1:100

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Image 4: Jurkat cells were subjected to SDS PAGE followed by western blot with FNab10030(LAT antibody) at dilution of 1:1000

Gene ID: 27040

Research Area: Metabolism

Uniprot ID: O43561