anti- LGR6 antibody

Product Description

anti- LGR6 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: Receptor for R-spondins that potentiates the canonical Wnt signaling pathway and acts as a marker of multipotent stem cells in the epidermis. Upon binding to R-spondins(RSPO1, RSPO2, RSPO3 or RSPO4), associates with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. In contrast to classical G-protein coupled receptors, does not activate heterotrimeric G-proteins to transduce the signal. May act as a tumor suppressor..

Immunogen: leucine-rich repeat-containing G protein-coupled receptor 6

Synonyms: FLJ14471, GPCR, LGR6, VTS20631

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, IHC, WB, FC

Recommended dilution: WB: 1:200-1:1000; IHC: 1:20-1:200

Image 1: Immunohistochemistry of paraffin-embedded human testis using FNab04766(LGR6 antibody) at dilution of 1:50

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Image 4: mouse testis tissue were subjected to SDS PAGE followed by western blot with FNab04766(LGR6 antibody) at dilution of 1:100

Gene ID: 59352

Research Area: Metabolism

Uniprot ID: Q9HBX8