Euro
British Pound
US Dollar
Product Description
anti- LRRC8D antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: Non-essential component of the volume-regulated anion channel(VRAC, also named VSOAC channel), an anion channel required to maintain a constant cell volume in response to extracellular or intracellular osmotic changes. The VRAC channel conducts iodide better than chloride and may also conduct organic osmolytes like taurine. Channel activity requires LRRC8A plus at least one other family member(LRRC8B, LRRC8C, LRRC8D or LRRC8E); channel characteristics depend on the precise subunit composition(PubMed:24790029, PubMed:26824658). LRRC8A and LRRC8D are required for the uptake of the drug cisplatin(PubMed:26530471). Mediates the import of the antibiotic blasticidin-S into the cell(PubMed:24782309)..
Immunogen: leucine rich repeat containing 8 family, member D
Synonyms: LRRC5
Reactivity: Human, Mouse, Rat
Tested Application: ELISA, WB
Recommended dilution:
Image 1:
Image 2: .
Image 3:
Image 4: HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab04862(LRRC8D antibody) at dilution of 1:400
Gene ID: 55144
Research Area: Metabolism
Uniprot ID: Q7L1W4
