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Product Description
anti- LRWD1 antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: Required for G1/S transition. Recruits and stabilizes the origin recognition complex(ORC) onto chromatin during G1 to establish pre-replication complex(preRC) and to heterochromatic sites in post-replicated cells. Binds a combination of DNA and histone methylation repressive marks on heterochromatin. Binds histone H3 and H4 trimethylation marks H3K9me3, H3K20me3 and H4K27me3 in a cooperative manner with DNA methylation. Required for silencing of major satellite repeats. May be important ORC2, ORC3 and ORC4 stability..
Immunogen: leucine-rich repeats and WD repeat domain containing 1
Synonyms: CENP-33, ORCA
Reactivity: Human
Tested Application: ELISA, WB
Recommended dilution:
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Image 4: human testis tissue were subjected to SDS PAGE followed by western blot with FNab04867(LRWD1 antibody) at dilution of 1:100
Gene ID: 222229
Research Area: Metabolism
Uniprot ID: Q9UFC0
