anti- MAGEA3 antibody

Product Description

anti- MAGEA3 antibody is available at Gentaur for Next week Delivery.

Purification: Protein A+G purification

Background: Proposed to enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. May enhance ubiquitin ligase activity of TRIM28 and stimulate p53/TP53 ubiquitination by TRIM28. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme(E2) at the E3:substrate complex. May play a role in embryonal development and tumor transformation or aspects of tumor progression. In vitro promotes cell viability in melanoma cell lines. Antigen recognized on a melanoma by autologous cytolytic T-lymphocytes..

Immunogen: melanoma antigen family A, 3

Synonyms: Antigen MZ2 D, Cancer/testis antigen 1.3, CT1.3, HIP8, HYPD, MAGE 3 antigen, MAGE3, MAGEA3, MAGE-A3, MAGEA6, melanoma antigen family A, 3, Melanoma associated antigen 3

Reactivity: Human

Tested Application: ELISA, WB, IHC

Recommended dilution: WB: 1:500-1:2000; IHC: 1:50-1:200

Image 1: Immunohistochemistry of paraffin-embedded human lung cancer tissue slide using FNab04937(MAGEA3 Antibody) at dilution of 1:200 heat mediated antigen retrieved with Tris-EDTA buffer(pH9).

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Image 4: mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab04937(MAGEA3 Antibody) at dilution of 1:2000

Gene ID: 4102

Research Area: Metabolism

Uniprot ID: P43357