Product Description
anti- MAGED1 antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: Involved in the apoptotic response after nerve growth factor(NGF) binding in neuronal cells. Inhibits cell cycle progression, and facilitates NGFR-mediated apoptosis. May act as a regulator of the function of DLX family members. May enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme(E2) at the E3:substrate complex. Plays a role in the circadian rythm regulation. May act as RORA co-regulator, modulating the expression of core clock genes such as ARNTL/BMAL1 and NFIL3, induced, or NR1D1, repressed..
Immunogen: melanoma antigen family D, 1
Synonyms: NRAGE
Reactivity: Human, Mouse, Rat
Tested Application: ELISA, WB, IHC, IF
Recommended dilution:
Image 1: Immunohistochemistry of paraffin-embedded human placenta using FNab04947(MAGED1 antibody) at dilution of 1:50
Image 2: .
Image 3:
Image 4: A549 cells were subjected to SDS PAGE followed by western blot with FNab04947(MAGED1 Antibody) at dilution of 1:1000
Gene ID: 9500
Research Area: Metabolism
Uniprot ID: Q9Y5V3