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Product Description
anti- MAML1 antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: Acts as a transcriptional coactivator for NOTCH proteins. Has been shown to amplify NOTCH-induced transcription of HES1. Enhances phosphorylation and proteolytic turnover of the NOTCH intracellular domain in the nucleus through interaction with CDK8. Binds to CREBBP/CBP which promotes nucleosome acetylation at NOTCH enhancers and activates transcription. Induces phosphorylation and localization of CREBBP to nuclear foci. Plays a role in hematopoietic development by regulating NOTCH-mediated lymphoid cell fate decisions..
Immunogen: mastermind-like 1(Drosophila)
Synonyms: KIAA0200
Reactivity: Human, Mouse, Rat
Tested Application: ELISA, WB
Recommended dilution:
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Image 4: PC-3 cells were subjected to SDS PAGE followed by western blot with FNab04956(MAK antibody) at dilution of 1:800
Gene ID: 9794
Research Area: Metabolism
Uniprot ID: Q92585
