anti- MAP2K4 antibody

Product Description

anti- MAP2K4 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: This gene encodes a member of the mitogen-activated protein kinase (MAPK) family. Members of this family act as an integration point for multiple biochemical signals and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation, and development. They form a three-tiered signaling module composed of MAPKKKs, MAPKKs, and MAPKs. This protein is phosphorylated at serine and threonine residues by MAPKKKs and subsequently phosphorylates downstream MAPK targets at threonine and tyrosine residues. A similar protein in mouse has been reported to play a role in liver organogenesis. A pseudogene of this gene is located on the long arm of chromosome X. Alternative splicing results in multiple transcript variants..

Immunogen: MAP2K4

Synonyms: JNKK, JNKK1, MAPKK4, MEK4, MKK4, PRKMK4, SAPKK-1, SAPKK1, SEK1, SERK1, SKK1

Reactivity: Human, mouse, Rat

Tested Application: ELISA, WB, IHC

Recommended dilution: WB: 1:500-1:2000; IHC: 1:50-1:500

Image 1: Immunohistochemistry of paraffin-embedded human breast cancer using FNab10073( MAP2K4 Antibody) at dilution of 1:100

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Image 4: Mcf-7 cells were subjected to SDS PAGE followed by western blot with FNab10073(MAP2K4 antibody) at dilution of 1:1000

Gene ID: 6416

Research Area: Metabolism

Uniprot ID: P45985