anti- MAPKBP1 antibody

Product Description

anti- MAPKBP1 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: MAP kinases play a significant role in many biological processes, including cell adhesion and spreading, cell differentiation and apoptosis. MAPKBP-1 (mitogen-activated protein kinase binding protein 1), also known as JNKBP-1, is a 1, 514 amino acid protein that contains twelve WD repeats. Induced by TRAF2 (TNF receptor-associated factor 2) and Tak1 (TGF-?-activated kinase 1), MAPKBP-1 is thought to act an adaptor protein for NF?B (nuclear factor ?-B) activation. MAPKBP-1 interacts with JNK3 and may promote TRAF2 polyubiquitination. MAPKBP-1 exists as six alternatively spliced variants and is encoded by a gene located on human chromosome 15. Human chromosome 15 houses over 700 genes and comprises nearly 3% of the human genome. Angelman syndrome, Prader-Willi syndrome, Tay-Sachs disease and Marfan syndrome are all associated with defects in chromosome 15-localized genes..

Immunogen: mitogen-activated protein kinase binding protein 1

Synonyms: JNKBP1, KIAA0596

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, WB, IHC

Recommended dilution: WB: 1:200 - 1:500; IHC: 1:50 - 1:100

Image 1: Immunohistochemistry of paraffin-embedded human stomach using FNab05000(MAPKBP1 antibody) at dilution of 1:100

Image 2: .

Image 3:

Image 4: mouse liver tissue were subjected to SDS PAGE followed by western blot with FNab05000(MAPKBP1 antibody) at dilution of 1:300

Gene ID: 23005

Research Area: Metabolism

Uniprot ID: O60336