Product Description
anti- MASP1 antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: Functions in the lectin pathway of complement, which performs a key role in innate immunity by recognizing pathogens through patterns of sugar moieties and neutralizing them. The lectin pathway is triggered upon binding of mannan-binding lectin(MBL) and ficolins to sugar moieties which leads to activation of the associated proteases MASP1 and MASP2. Functions as an endopeptidase and may activate MASP2 or C2 or directly activate C3 the key component of complement reaction. Isoform 2 may have an inhibitory effect on the activation of the lectin pathway of complement or may cleave IGFBP5..
Immunogen: mannan-binding lectin serine peptidase 1(C4/C2 activating component of Ra-reactive factor)
Synonyms: CRARF, CRARF1, PRSS5
Reactivity: Human
Tested Application: ELISA, WB
Recommended dilution:
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Image 4: HeLa cells were subjected to SDS PAGE followed by western blot with FNab05021( MASP1 Antibody) at dilution of 1:300
Gene ID: 5648
Research Area: Metabolism
Uniprot ID: P48740