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Product Description
anti- MCM8 antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: Component of the MCM8-MCM9 complex, a complex involved in homologous recombination repair following DNA interstrand cross-links and plays a key role during gametogenesis. The MCM8-MCM9 complex probably acts as a hexameric helicase downstream of the Fanconi anemia proteins BRCA2 and RAD51 and is required to process aberrant forks into homologous recombination substrates and to orchestrate homologous recombination with resection, fork stabilization and fork restart. May also play a non-essential for DNA replication: may be involved in the activation of the prereplicative complex(pre-RC) during G(1) phase by recruiting CDC6 to the origin recognition complex(ORC). Binds chromatin throughout the cell cycle..
Immunogen: minichromosome maintenance complex component 8
Synonyms: C20orf154
Reactivity: Human, Mouse, Rat
Tested Application: ELISA, WB
Recommended dilution:
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Image 4: NIH/3T3 cells were subjected to SDS PAGE followed by western blot with FNab05063(MCM8 antibody) at dilution of 1:300
Gene ID: 84515
Research Area: Metabolism
Uniprot ID: Q9UJA3
