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Product Description
anti- MDC1 antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: The protein encoded by this gene contains an N-terminal forkhead domain, two BRCA1 C-terminal (BRCT) motifs and a central domain with 13 repetitions of an approximately 41-amino acid sequence. The encoded protein is required to activate the intra-S phase and G2/M phase cell cycle checkpoints in response to DNA damage. This nuclear protein interacts with phosphorylated histone H2AX near sites of DNA double-strand breaks through its BRCT motifs, and facilitates recruitment of the ATM kinase and meiotic recombination 11 protein complex to DNA damage foci..
Immunogen: mediator of DNA damage checkpoint 1
Synonyms: KIAA0170, NFBD1
Reactivity: Human
Tested Application: ELISA, IHC, WB
Recommended dilution: WB: 1:500 - 1:2000; IHC: 1:100 - 1:200
Image 1: Immunohistochemistry of paraffin-embedded human prostate cancer using FNab05072(MDC1 Antibody) at dilution of 1:100
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Image 4: HeLa cells were subjected to SDS PAGE followed by western blot with FNab05072(MDC1 antibody) at dilution of 1:1000
Gene ID: 9656
Research Area: Metabolism
Uniprot ID: Q14676
