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Product Description
anti- MDM2 antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: This gene encodes a nuclear-localized E3 ubiquitin ligase. The encoded protein can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. This gene is itself transcriptionally-regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript variants, many of which may be expressed only in tumor cells..
Immunogen: Mdm2 p53 binding protein homolog ( Mouse )
Synonyms: ACTFS
Reactivity: Human, Mouse, Rat
Tested Application: ELISA, IHC, WB, IF
Recommended dilution: WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200
Image 1: Immunohistochemistry of paraffin-embedded human stomach using FNab05077(MDM2 antibody) at dilution of 1:100
Image 2: .
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Image 4: HT-29 cells were subjected to SDS PAGE followed by western blot with FNab05077(MDM2 antibody) at dilution of 1:1000
Gene ID: 4193
Research Area: Metabolism
Uniprot ID: Q00987
