anti- MICA antibody

Product Description

anti- MICA antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: This gene encodes the highly polymorphic major histocompatability complex class I chain-related protein A. The protein product is expressed on the cell surface, although unlike canonical class I molecules it does not seem to associate with beta-2-microglobulin. It is a ligand for the NKG2-D type II integral membrane protein receptor. The protein functions as a stress-induced antigen that is broadly recognized by intestinal epithelial gamma delta T cells. Variations in this gene have been associated with susceptibility to psoriasis 1 and psoriatic arthritis, and the shedding of MICA-related antibodies and ligands is involved in the progression from monoclonal gammopathy of undetermined significance to multiple myeloma. Alternative splicing of this gene results in multiple transcript variants..

Immunogen: MHC class I polypeptide-related sequence A

Synonyms: PERB11.1

Reactivity: Human, Mouse

Tested Application: ELISA, WB, IHC

Recommended dilution: WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

Image 1: Immunohistochemistry of paraffin-embedded human stomach using FNab05176(MICA antibody) at dilution of 1:100

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Image 4: K-562 cells were subjected to SDS PAGE followed by western blot with FNab05176(MICA antibody) at dilution of 1:1000

Gene ID: 100507436

Research Area: Metabolism

Uniprot ID: Q29983