Product Description
anti- MICAL1 antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: Monooxygenase that promotes depolymerization of F-actin by mediating oxidation of specific methionine residues on actin. Acts by modifying actin subunits through the addition of oxygen to form methionine-sulfoxide, leading to promote actin filament severing and prevent repolymerization(Probable). Acts as a cytoskeletal regulator that connects NEDD9 to intermediate filaments. Also acts as a negative regulator of apoptosis via its interaction with STK38 and STK38L; acts by antagonizing STK38 and STK38L activation by MST1/STK4..
Immunogen: microtubule associated monoxygenase, calponin and LIM domain containing 1
Synonyms: MICAL, MICAL 1, MICAL1, NICAL
Reactivity: Human, Mouse
Tested Application: ELISA, WB, IHC, IP, FC
Recommended dilution: WB: 1:1000-1:4000; IP: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:50-1:500
Image 1: Immunohistochemistry of paraffin-embedded human lung using FNab05177(MICAL1 antibody) at dilution of 1:100
Image 2: Immunofluorescent analysis of ( -20°C Ethanol) fixed HeLa cells using FNab05177 (MICAL1 antibody) at dilution of 1:50 and Alexa Fluor 488-Conjugated Goat Anti-Rabbit IgG(H+L).
Image 3: IP result of anti-MICAL1(IP: FNab05177, 5ug; Detection: FNab05177 1:1000) with Hela cells lysate 2000 ug
Image 4: Jurkat cells were subjected to SDS PAGE followed by western blot with FNab05177(MICAL1 antibody) at dilution of 1:1000
Gene ID: 64780
Research Area: Metabolism
Uniprot ID: Q8TDZ2