Product Description
anti- MICAL2 antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: Nuclear monooxygenase that promotes depolymerization of F-actin by mediating oxidation of specific methionine residues on actin and regulates the SRF signaling. Acts by modifying nuclear actin subunits through the addition of oxygen to form methionine-sulfoxide, leading to promote actin filament severing and prevent repolymerization. Acts as a key regulator of the SRF signaling pathway elicited by nerve growth factor and serum: mediates oxidation and subsequent depolymerization of nuclear actin, leading to increase MKL1/MRTF-A presence in the nucleus and promote SRF:MKL1/MRTF-A-dependent gene transcription. Does not activate SRF:MKL1/MRTF-A through RhoA..
Immunogen: microtubule associated monoxygenase, calponin and LIM domain containing 2
Synonyms: KIAA0750, MICAL2PV1, MICAL2PV2
Reactivity: Human, Mouse, Rat
Tested Application: ELISA, IHC, IF
Recommended dilution:
Image 1: Immunohistochemistry of paraffin-embedded human stomach cancer slide using FNab05178(MICAL2 Antibody) at dilution of 1:50
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Gene ID: 9645
Research Area: Metabolism
Uniprot ID: O94851