anti- MINK1 antibody

Product Description

anti- MINK1 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: Serine/threonine kinase which acts as a negative regulator of Ras-related Rap2-mediated signal transduction to control neuronal structure and AMPA receptor trafficking. Required for normal synaptic density, dendrite complexity, as well as surface AMPA receptor expression in hippocampal neurons. Can activate the JNK and MAPK14/p38 pathways and mediates stimulation of the stress-activated protein kinase MAPK14/p38 MAPK downstream of the Raf/ERK pathway. Phosphorylates: TANC1 upon stimulation by RAP2A, MBP and SMAD1. Has an essential function in negative selection of thymocytes, perhaps by coupling NCK1 to activation of JNK1. Isoform 4 can activate the JNK pathway. Involved in the regulation of actin cytoskeleton reorganization, cell-matrix adhesion, cell-cell adhesion and cell migration..

Immunogen: misshapen-like kinase 1(zebrafish)

Synonyms: B55, MAP4K6,

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, WB, IHC

Recommended dilution:

Image 1: Immunohistochemistry of paraffin-embedded human lymphoma tissue slide using FNab05191(MINK1 Antibody) at dilution of 1:50

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Image 4: mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab05191(MINK1 antibody) at dilution of 1:300

Gene ID: 50488

Research Area: Metabolism

Uniprot ID: Q8N4C8