anti- MMP14 antibody

Product Description

anti- MMP14 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily; each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. This protein activates MMP2 protein, and this activity may be involved in tumor invasion..

Immunogen: matrix metallopeptidase 14 (membrane-inserted)

Synonyms: MMP-14

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, WB, IHC

Recommended dilution: WB: 1:500 - 1:2000; IHC: 1:50 - 1:100

Image 1: Immunohistochemistry of paraffin-embedded human liver cancer using FNab05236(MMP14 Antibody) at dilution of 1:100

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Image 4: mouse liver tissue were subjected to SDS PAGE followed by western blot with FNab05236(MMP14 antibody) at dilution of 1:1000

Gene ID: 4323

Research Area: Metabolism

Uniprot ID: P50281