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Product Description
anti- MSH3 antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: Component of the post-replicative DNA mismatch repair system(MMR). Heterodimerizes with MSH2 to form MutS beta which binds to DNA mismatches thereby initiating DNA repair. When bound, the MutS beta heterodimer bends the DNA helix and shields approximately 20 base pairs. MutS beta recognizes large insertion-deletion loops(IDL) up to 13 nucleotides long. After mismatch binding, forms a ternary complex with the MutL alpha heterodimer, which is thought to be responsible for directing the downstream MMR events, including strand discrimination, excision, and resynthesis..
Immunogen: mutS homolog 3
Synonyms: DUC1, DUG
Reactivity: Human
Tested Application: ELISA, WB
Recommended dilution:
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Image 4: HeLa cells were subjected to SDS PAGE followed by western blot with FNab05373(MSH3 antibody) at dilution of 1:1000
Gene ID: 4437
Research Area: Metabolism
Uniprot ID: P20585
