Product Description
anti- MSL1 antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: Component of histone acetyltransferase complex responsible for the majority of histone H4 acetylation at 'Lys-16'(H4K16ac) which is implicated in the formation of higher-order chromatin structure. Greatly enhances MSL2 E3 ubiquitin ligase activity, promoting monoubiquitination of histone H2B at 'Lys-34'(H2BK34Ub). This modification in turn stimulates histone H3 methylation at 'Lys-4'(H3K4me) and 'Lys-79'(H3K79me) and leads to gene activation, including that of HOXA9 and MEIS1. In the MSL complex, acts as a scaffold to tether MSL3 and KAT8 together for enzymatic activity regulation..
Immunogen: male-specific lethal 1 homolog(Drosophila)
Synonyms: MSL1L1
Reactivity: Human
Tested Application: ELISA, WB
Recommended dilution:
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Image 4: HeLa cells were subjected to SDS PAGE followed by western blot with FNab05379( MSL1 Antibody) at dilution of 1:600
Gene ID: 339287
Research Area: Metabolism
Uniprot ID: Q68DK7