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Product Description
anti- MYO9B antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Binds actin with high affinity both in the absence and presence of ATP and its mechanochemical activity is inhibited by calcium ions(PubMed:9490638). Also acts as a GTPase activator for RHOA(PubMed:9490638, PubMed:26529257). Plays a role in the regulation of cell migration via its role as RHOA GTPase activator. This is regulated by its interaction with the SLIT2 receptor ROBO1; interaction with ROBO1 impairs interaction with RHOA and subsequent activation of RHOA GTPase activity, and thereby leads to increased levels of active, GTP-bound RHOA(PubMed:26529257)..
Immunogen: myosin IXB
Synonyms: MYR5
Reactivity: Human, Mouse, Rat
Tested Application: ELISA, WB, IP
Recommended dilution:
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Image 4: mouse thymus tissue were subjected to SDS PAGE followed by western blot with FNab05509( MYO9B Antibody) at dilution of 1:600
Gene ID: 4650
Research Area: Metabolism
Uniprot ID: Q13459
