anti- NDC80 antibody

Product Description

anti- NDC80 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity(PubMed:9315664, PubMed:12351790, PubMed:14654001, PubMed:14699129, PubMed:15062103, PubMed:15235793, PubMed:15239953, PubMed:15548592, PubMed:16732327). Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore(PubMed:15548592). The NDC80 complex synergistically enhances the affinity of the SKA1 complex for microtubules and may allow the NDC80 complex to track depolymerizing microtubules(PubMed:23085020)..

Immunogen: NDC80 homolog, kinetochore complex component(S. cerevisiae)

Synonyms: HEC, HEC1, KNTC2

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, WB, IHC, IP

Recommended dilution:

Image 1: Immunohistochemistry of paraffin-embedded human brain using FNab05599(NDC80 antibody) at dilution of 1:100

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Image 4: A2780 cells were subjected to SDS PAGE followed by western blot with FNab05599(NDC80 antibody) at dilution of 1:500

Gene ID: 10403

Research Area: Metabolism

Uniprot ID: O14777